The Hofmann Rearrangement. IV. Kinetic Isotope Effect ofN-Chlorobenzamide
نویسندگان
چکیده
منابع مشابه
Hippuric acid analysis of urine using the Hofmann rearrangement.
1. METHOD FOR THE determination of hippuric acid based on the formatioll of a bromine derivative was deScrii)ed by Deniges (1). This bromine derivative has been determined in our laboratory to be Nbromobenzamide. N-bromobenzamide is the hydrolysis and bromination product of hippuric acid, being produced when hippuric acid is subjected to the Hofniann rearrangement, tile first step of which is a...
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In the clusters [Ru3(micro(3)-NPPh(3))(micro(3)-OSiMe(3))(micro-X)(micro(C,O)-OC[double bond]NPPh(3))(micro-CO)(CO)6] (X = NCO, 2; X = Cl, 3), which were prepared by a pyrolytic reaction of Ph(3)PNSiMe(3) with Ru(3)(CO)12, the ligands result from a cluster-mediated pseudo-Hofmann rearrangement involving the micro-NCO, micro(C,O)-Ph(3)P[double bond]N-CO and micro(3)-NPPh(3) fragments.
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متن کاملKinetic isotope effects
Kinetic isotope effects (KIEs) [9] are the effects on chemical reaction rates caused by isotopic substitution in the reacting system. KIEs report on bonding changes to the isotopic atom(s) when going from reactant state to transition state (TS). KIE studies are therefore of great use in solving mechanistic problems such as: (i) concerted or stepwise reaction? (ii) which is the rate limiting ste...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1971
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.44.2776